Type of Fatty Acid intake, serum Lipid and Lipoprotein levels in relation to Creatinine and GFR

Azad Bakht L, Mirmiran P, Esmail Zadeh A, Ghabili MJ, Azizi F, (2004) Type of Fatty Acid intake, serum Lipid and Lipoprotein levels in relation to Creatinine and GFR. Journal of Kerman University of Medical Sciences, 11 (1). ISSN 1023-9510

mjku8211114.pdf - Published Version

Download (456kB) | Preview
Official URL: http//jkmu.kmu.ac.ir


Correlation between fatty acids intake, serum lipid and lipoproteins with serum creatinine and kidney function in patients with renal failure has been suggested by other investigators. This relationship has not been reported for all types of fatty acids. This study was conducted to determine the association of the consumption of different type of fatty acids, serum lipid and Lipoproteins with serum creatinine and glumerular filtration rate (GFR) in healthy adult subjects residing in district 13 of Tehran. There were 15005 subjects participated in TLGS. 1470 persons were randomly selected for nutritional assessment. After excluding under- and over-reporter 486 subjects aged over 20 years remained in the study. Dietary data were collected by two 24-hour dietary recalls. Serum creatinine, total cholesterol, triglyceride and HDL were measured by Selectra 2 autoanalyzer after 12 hour fasting. GFR was calculated based on serum creatinine. Mean (±SD) of serum creatinine, cholesterol, triglyceride HDL and LDL levels and GFR were 1.04±0.16, 201±41, 153±125, 43±10, 128±37 mg/dl and 99±19 ml/min respectively. Subjects with saturated fatty acids intake of more than 10% of calorie had higher levels of serum creatinine versus the others (P<0.01, 10.8±0.009 vs. 1.03±0.2). People with oleic and linoleic acid intake of more than 10% and 1% of calorie, respectively, had higher levels of serum creatinine and GFR (P<0.01). There were significant correlation between serum cholesterol, LDL, HDL, and triglyceride with serum creatinine (P<0.05, P<0.05, P<0.001, P<0.001 respectively). According to observed correlations the control of intake of desirable amount of fatty acids and serum lipid and lipoproteins level is necessary for renal health. Keywords: Fatty acids intake, Cholesterol, Triglyceride, LDL-c, HDL-c, Serum creatinine, GFR

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: journals journals journals
Date Deposited: 10 Jan 2016 08:40
Last Modified: 10 Jan 2016 08:40
URI: http://eprints.kmu.ac.ir/id/eprint/24516

Actions (login required)

View Item View Item