Fasting Blood Glucose and Insulin Level in Opium Addict versus Non-Addict Individuals

Gozashti, MH and Yazdi, F and Salajegheh, P and Dehesh, MM and Divsalar, K (2015) Fasting Blood Glucose and Insulin Level in Opium Addict versus Non-Addict Individuals. Addict Health, 7 (1-2). pp. 54-9.

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BACKGROUND: Many of lay person believe that opium lowers blood glucose. However some studies show the opposite results. In this study, we tried to evaluate the effect of opium on blood glucose and insulin resistance. METHODS: This comparative study including 53 addicts in case groups who used opium just in the form of smoking and 55 non-addicts in a control group, took part in the study, after proving not to be opium users. After taking blood samples, their fasting blood glucose (FBG), fasting blood insulin and lipid profiles were evaluated. Furthermore, insulin resistance index was analyzed via the homeostatic model assessment of insulin resistance (HOMA-IR) formula with the cut-off points of 7.2 and 7.1. FINDINGS: Age and gender were not significantly different between the groups. There was no significant difference regarding the prevalence of insulin resistance between the two groups, according to the cut-off points of 7.1 and 7.2 (P = 0.196 and P = 0.248, respectively). Mean insulin resistance index was not significantly different between the two groups (P = 0.325). In the case group, fasting blood insulin was considerably lower (P = 0.025) and fasting blood sugar (FBS) was significantly higher (P = 0.016) than the control group. CONCLUSION: According to the level of insulin and FBS in addicts, it does not seem that opium has a significant effect on reducing the blood glucose and insulin resistance.

Item Type: Article
Uncontrolled Keywords: Blood sugar; Insulin resistance; Opium addiction
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RZ Other systems of medicine
Depositing User: azam bazrafshan bazrafshan
Date Deposited: 20 Dec 2015 10:50
Last Modified: 20 Dec 2015 10:50

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